化痰截哮汤治疗慢性阻塞性肺疾病急性发作（痰瘀伏肺证）临床研究

摘要

Objective :The objective of the study is to observe the therapeutic effects of Huatan jiexiao De‐cotion on AECOPD and its influence on inflammation indexes .Methods:The experiment randomly divided 181 pa‐tients diagnosed with AECOPD into two groups .Patients in both groups were treated with routine western medi‐cine .Huatan jiexiao Decotion was added to the treatment of patients in control group .The total effectire rate of the treatment group was 86 .81% ,which was better than that of control group(71 .11% )(P<0 .05) .The scores of CRP、PCT and clinical Synptoms decreased significantly after treatment in both groups (P< 0 .05) .Five days after the treatment ,there was significant decrease in sputum integral in control group (P<0 .05) .Ten days after the treat‐ment ,there was significant decrease in sputum integral、asthma、chest distress integral in control group (P<0 .05) . Ater the treatment there was also significant decrease in CRP 、PCT level which was statistically significant (P<0 . 05) .Conclusion :the therapeutic effects of Huatan jiexiao Decotion on AECOPD disease are significant ,which msy be related to the decrease of CRPand PCT .%目的：观察化痰截哮汤治疗 A EC O PD的疗效及其对炎症指标的影响。方法：选取A EC O PD （痰瘀伏肺证）患者181例，随机分为治疗组和对照组。对照组用西医常规方法治疗，治疗组在此基础上加用化痰截哮汤。治疗10d后，比较两组临床疗效及治疗前后症候积分、CRP、PCT的变化。结果：治疗组总有效率86．81％，优于对照组71．11％（ P＜0．05）。两组治疗后较同组治疗前CRP、PCT 及临床症候积分数值下降明显（P＜0．01，P＜0．05）。两组治疗后组间比较，治疗组治疗后第5天痰量积分，第10天痰量、气喘、胸闷积分较对照组同期明显降低（ P＜0．05），治疗组治疗后CRP、PCT 数值较对照组下降明显（P＜0．05）。结论：化痰截哮汤协同治疗AECOPD疗效好，可能与其明显降低CRP及PCT 水平有关。