阿苯达唑及其重要中间体4-丙硫基邻苯二胺的合成 ——兼评芳香硝基物的选择性还原

摘要

在对阿苯达唑的合成路线简介的基础上，对由2-硝基-4-丙硫基苯胺制4-丙硫基邻苯二胺过程中硝基转化为氨基的方法作了简要评述。针对现有工艺的缺点，提出了芳香硝基物选择还原的环境友好生产工艺新思路。%A brief introduction was made on the synthesis of albendazole.The ways of transforming nitroarenes to corresponding amine compounds were discussed. Aimed at the pollution problem presently, a new idea of environmental friendly process for the selective reduction of nitroarenes was proposed.