柔红霉素预防后囊膜混浊的临床研究

摘要

Objective To observe the clinical effect of Daurorubicin (DNR)preventing the posterior capsule opacification(PCO).Methods Sixty-two eyes with cataract were divided into the experimental group (28 eyes) and the control group (34 eyes). All the patients were performed the extracapsular cataract extraction(ECCE) with or without posterior chamber intraocular lens implant (PC-IOL). The infusing liquid with DNR(7.5mg.L-1) was infused into the anterior chamber in the experimental group operatively; The Ringer liquid was infused into the anterior chamber in the control. The PCO was observed postoperatively.Results The occurence rate of PCO in the experimental group was obviously lower than that in the control (P＜0.05). After three months postoperatively, the patients' mean visual acuity in the experimental group was 4.47±0.24 and that in the control group was 4.66±0.26(P＜0.05). Conclusion DNR can effectively prevent the PCO, and has a good clinical value.%目的 观察柔红霉素预防后囊膜混浊的临床效果。方法 对62只患白内障眼行白内障囊外摘出术及白内障囊外摘出并后房型人工晶状体植入术，分为实验组和对照组，实验组28眼，术中前房灌注液加入柔红霉素(7.5mg.L-1)，对照组34眼，术中使用Ringer液，术后观察后囊膜混浊情况。结果 实验组后囊膜混浊发生率明显低于对照组(P＜0.05)，术后3mo，实验组平均视力为4.47±0.24，对照组为4.66±0.26(P＜0.05)。结论 柔红霉素能有效预防后囊膜混浊，具有临床使用价值。