单纯强阿片类治疗肺癌与姑息性化疗联合强阿片类治疗肺癌的生活质量对比分析

摘要

Objective To compare the clinical efficacy of simple strong opioids and palliative chemotherapy combined with strong opioids in the treatment of lung cancer. Methods Randomly selected from July 2011 to February 2014 admitted to our hospital 80 cases of advanced cancer patients, divided into control group and observation group, each with 40 cases in each, morphine, fentanyl for strong opioids, choose S-1 for palliative chemotherapy drugs. Control group of patients treated with strong opioid therapy, the observation group patients were given palliative chemotherapy combined with strong opioid drugs for treatment, comparative analysis of lung cancer patient appetite, sleep, pain, quality of life score. Results The quality of life of the patients in the observation group was significantly better than that in the control group, the difference was statistically significant (P<0.05). Conclusion In the clinical treatment of lung cancer, the combined use of strong opioids and palliative chemotherapy can effectively improve the quality of life of patients, which has the value of clinical application.%目的：对比分析单纯强阿片类与姑息性化疗联合强阿片类治疗肺癌生活质量的临床疗效。方法：随机抽取2011年7月～2014年2月我院收治的80例中晚期癌症患者，平均分成对照组和观察组，每组各40例，选择吗啡、芬太尼为强阿片类药物，选择替吉奥为姑息性化疗药物。对照组患者单纯采用强阿片类药物治疗，观察组给予患者姑息性化疗联合强阿片类药物进行治疗，对比分析肺癌患者食欲、睡眠、疼痛等生活质量评分。结果：观察组肺癌患者的生活质量评分明显优于对照组，差异有统计学意义(P＜0.05)。结论：在肺癌的临床治疗中，强阿片类药物与姑息性化疗的联合使用可有效提高患者生活质量水平，具有临床推广价值。