一例泰迪犬冠状病毒感染伴发急性肺水肿的病理诊断报告

摘要

A four-months-old Teddy dog died suddenly during the intravenous fluid administration treatment of coronavirus infection.The autopsy results showed that there were several obvious gross lesions especially in the lung and heart.Histopathological results showed that there were severe lesions of diffusive pulmonary congestion and edema and local necrosis of myocardium.Through the clinical history,necropsy and histopathological observation,the dog was diagnosed as canine coronavirus infection accompanied with acute pulmonary edema,which finally caused the death of the dog.The systematic pathological and histopathological analysis were conducted and discussed in this article in order to provide practical suggestion for the diagnosis and treatment of the similar cases.%某宠物主人送检1只4月龄泰迪犬,初步确诊为冠状病毒感染,于输液过程中突然死亡.剖检可见整个肺脏呈深红色,肺叶边缘呈粉红色,切面深红色,支气管断端有大量红色液体渗出;剖开气管可见其浆膜面呈暗红色,腔内充满红色清亮液体;心脏左右心室扩张,质地柔软,心尖钝圆,呈心力衰竭心.对各个脏器取材进行病理组织学观察,主要病变表现为肺脏弥漫性淤血、水肿,心肌纤维局部溶解坏死.诊断该犬因感染冠状病毒后初次洗澡应激加重病情,并且随着大量静脉输液导致或加剧急性肺水肿发生,最终造成该犬急性死亡.对该病例进行了系统地病理剖检和组织病理学观察,为犬科动物和其他动物发生类似病症提供一定的参考.