目的:利用共振频率测量仪(Osstell)连续监测骨愈合期种植体稳定性变化与早期边缘骨吸收的关系.方法:本研究于2010-2011年期间根据纳入及排除标准连续纳入32名成年男性患者作为实验对象共植入45枚Strauman种植体,每名患者选择一颗( 4.8mm× 10mm)种植体,共计32颗种植体,种植区位于下颌后牙(骨质均为Ⅱ或Ⅲ类骨).利用共振频率分析仪(Osstell)测量种植体的稳定性,测量时间点为植入时以及术后第1,2,3,4,6,8,12周.另外,影像学分析测量32颗种植体12周时的边缘骨吸收；结果:本实验中所有种植体在12周均实现骨结合,并成功完成种植修复.通过重复性方差分析,见表1,在种植体植入时,初期稳定系数( ISQ)均值为(79.03+ 6.756).术后一周,种植体稳定系数(ISQ)均值均呈下降趋势,至术后第2周时达到最低点,与植入时稳定性有统计学差异(P＜0.05).从术后第3周开始种植体稳定系数( ISQ)均值逐渐上升.其中,稳定系数(ISQ)均值在第6周时与第12周无统计学差异,已达到延期稳定期.32颗种植体在第12周的边缘骨吸收均值为(0.86+ 0.068mm),而在第12周的种植体的稳定系数均值与种植体植入时的稳定系数均值无统计学差异.结论:本实验通过共振频率测量仪(OsstellTM)连续监测,目前的结果认为种植体愈合期边缘骨吸收对种植体愈合期稳定性变化没有影响.%The aim of this study was to monitor the changes in the stability-related bone loss during the early healing period. Methods: 32consecutive adult males with a partial edentulous in the posterior mandible were recruited according to the inclusion and exclusion criteria. 45 Straumann dental implants were placed and one implant per person, totally 32 implants (4.8mm× 10mm). The implant stability was measured by RFA at implant insertion, 1,2, 3,4, 6, 8 and 12 weeks post-operatively. In addition, marginal bone loss was also investigated. Results: All the implants achieved osseintegration, uneventfully within the investigation of 12 weeks. At implant installation, the mean implant stability quotient (ISQ) value is (79.03 ± 6.756). A decrease trend in ISQ values within the first 2 weeks followed by an increase until week 12 was observed. In the secondary stability phase the increasing slope of ISQ values reaching a plateau by the point of 6 weeks. At 6andl2-week interval, the ISQ remained in a steady state and not statistically significant. In the present study, the marginal bone loss observed was (0.86± 0.068mm) within the healing period of 12 weeks. However, in the present study, at 12 weejc and implants installation no significant difference of ISQ values could be found. Conclusions: There were no correlation between the marginal bone loss and the change of implant stability.
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