盐酸环丙沙星在中华绒螯蟹体中的衰减研究

摘要

采用超高效液相色谱-质谱串联法,研究了不同养殖条件下盐酸环丙沙星在中华绒螯蟹体内的残留消除规律.结果表明,盐酸环丙沙星在中华绒螯蟹体内衰减消除较慢,休药35d后各组实验蟹体内的盐酸环丙沙星残留均远高于仪器检测限;各组实验蟹体内盐酸环丙沙星残留衰减消除速率总体表现为,28℃条件下的衰减消除速率快于22℃;五期幼蟹的衰减消除速率快于扣蟹;室外开放水域中的消除速率快于室内条件.%The elimination of ciprofloxacinum residue in Chinese mitten crab Eriocheir sinensis under different culture conditions was studied by using Ultra Performance Liquid Chromatography coupled with Mass Spectrometry (UPLC-MS).The results showed that the elimination was so slow that even at 35-day after administration, the levels of ciprofloxacinum residue in all groups of E.sinensis were higher than the instrument detection limit.The elimination rate was faster at 28℃ than at 22℃, in the fifth stage larvae than in the button crabs, and in outdoor open water than the indoor environment.