苏灵注射液与邦亭注射液对结直肠癌术后止血疗效的比较

摘要

Objective To compare the hemostasis effect of haemocoagulase agkistrodon for injection and he-mocoagulase halys for injection on hemorrhage after resection of colorectal cancer,and provide refeprences for clinical medication. Methods Sixty patients in the department of colorectal surgery of our hospital from January 2014 to Janu-ary 2015 were divided into 2 groups. Group A (n=30) was given 2 U of haemocoagulase agkistrodon for injection di-luted with 2~4 mL NS iv,once daily; group B (m=30) was given 2 U of hemocoagulase halys for injection diluted with 20 mL NS iv,twice daily. The hemostasis efficacy of the two groups was compared. Results The total effective rate of group A was higher than that of group B (93. 3% vs. 73. 3%,P<0. 05). There was no significant difference between the two groups in body temperature,blood loss,and bleeding time (P>0. 05). Conclusion The hemostasis effect of haemocoagulase agkistrodon for injection on hemorrhage after resection of colorectal cancer is better than that of hemocoagulase halys for injection with higher effective rate and has less adverse reaction.%目的：比较苏灵注射液与邦亭注射液对结直肠癌术后临床止血的效果,为临床用药提供参考。方法随机将2014年1月至2015年1月期间我院结直肠外科行手术治疗的60例结直肠癌术后患者分成A组(苏灵注射液组)和B组(邦亭注射液组),每组30例。 A组给予苏灵注射液2 U用生理盐水2~4 mL稀释后静脉注射,1次/d；B组给予邦亭静脉注射2 U用生理盐水20 mL稀释后静脉注射,2次/d。连用3 d后比较两组药物的临床止血效果。结果治疗后A组总有效率为93．3%,B组为73．3%,两组总有效率比较差异有统计学意义(P<0．05)；在不良反应方面两组比较差异无统计学意义(P>0．05)。结论苏灵注射液止血效果优于邦亭注射液,具有有效率高、不良反应少的优点。