目的 探讨肿瘤患者医院内感染的临床特点及危险因素,为肿瘤患者,特别是恶性肿瘤患者预防医院感染的发生提供理论依据.方法 对某三级肿瘤专科医院的82318例住院患者中发生医院内感染的796例病例进行回顾性分析,采用SPSS 18.0软件进行基本资料的描述和危险因素的统计分析.结果 本院医院感染率为0.97%,纳入分析患者的性别、平均年龄、年龄(28 d)、手术、抗菌药物治疗和抗肿瘤治疗等比较,差异有统计学意义(P28 d),surgery,antibiotic therapy and anti-tumor therapy were analyzed by Chi-square test,and the differences were statistically significant (P<0. 05). The most common infection site was respiratory tract (n=408,51%),followed by abdomen and digestive tract (n=145, 18%),surgical site (n=104,13%) and urinary tract (n =53,7%). In the 535 cases of positive samples,the main pathogenic bacteria was gram-negative bacilli (n=332,62. 06%),followed by fungus (n=95,17. 75%),mainly be-ing candida albicans. Conclusion Male,advanced age,long hospitalization time,radiotherapy,anti-tumor therapy are the risk factors of nosocomial infection in tumor hospitals.
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