CT-MRI融合技术在头颈部肿瘤GTV勾画中应用的研究

摘要

Objective To compare the difference of the CT,MRI and CT - MRI fusion imaging,investigate the advantages of CT - MRI fusion imaging for delineation of target areas in head and neck tumor. Methods The two images for per patient in 35 patients with head and neck cancer were received through CT, MRI scans and image fusion software, and the same physician on the same patient at the same time period delineated the target areas based on CT,MRI and image fusion to compare their tumor target volume( Gross Tumor Volume,GTV ) of the primary lesion. Results GTVCT ,GTVMRI ,GTVCT-MRI average were 21. 22 ± 1.56,23.64 ± 1.30,29.08 ± 2.09 cm3 , GTVCT compared with GTVMRI( t = 7. 05, P < 0. 01 ), GTVCT_MRI compared with GTVCT ( t = - 17. 82 ,P < 0. 01 ); GTVCT _ MKI compared with GTVMRI(t= 13.08,P<0.01 ). Conclusion The delineation of CT - MRI fusion for the tumor target areas was broader than the MRI or CT images alone in the head and neck cancer,CT - MRI fusion imaging technology can improve the accuracy of the target outline and more conducive to guide the implementation of precise radiotherapy.%目的 比较CT、MRI和CT-MRI融合技术在头颈肿瘤靶区勾画中的差异,探讨CT-MRI融合技术在头颈肿瘤靶区勾画中的优势.方法 35位头颈部肿瘤患者,通过CT、MRI扫描,利用图像融合软件得到每位患者的两幅图像;同一医生对同一患者在同一时间段内依据CT、MRI和融合图像勾画出靶区,比较原发病灶的肿瘤靶区的体积(Gross tumor volume,GTV).结果 GTVCT、GTVMRI、GTVCT-MRI的平均值分别为(21.22±1.56)cm3、(23.64±1.30)cm3、(29.08±2.09)cm3,GTVCT与GTVMRI比较(t=7.05,P＜0.01),GTVCT-MRI与GTVCT比较(t=-17.82,P＜0.01);GTVCT-MRI与GTVMRI比较(t=13.08,P＜0.01).结论 CT-MRI融合图像的头颈部肿瘤勾画靶区比单独MRI或CT图像的头颈部肿瘤勾画靶区更广,CT-MRI融合图像技术可提高靶区勾画的准确性,更利于指导精确放疗的实施.