Objective To investigate the one-year stroke event situation in patients with non-valvular atrial fibrillation associ-ated with hypertension in Chengdu area during the period between 2013 and 2015 and explore the risk factors.Methods After one-year follow-up,the patients were divided into stroke group and non-stroke group according to whether stroke occurred or not.The risk factors of stroke were analyzed by using multivariate logistic regression model.Results We selected 495 cases of non-valvular atrial fi-brillation with hypertension.Of the patients,466 had CHA2DS2-VASc ≥2,in which 74 were treated with anticoagulant therapy with 14.9% of anticoagulant treatment rate.There were 45 cases of ischemic stroke with 9.1% of incidence of stroke.Multivariate logistic regression analysis showed that age,female and smoking were the risk factors of ischemic stroke,and anticoagulant therapy was the pro-tective factor for the patients.Conclusion The incidence of ischemic stroke of patients with atrial fibrillation accompanied by hyperten-sion is higher within 1 year while the rate of anticoagulation therapy is low.Anticoagulant therapy can reduce the incidence of ischemic stroke,and age,female and smoking were the risk factors for ischemic stroke.%目的 调查成都地区2013~2015年非瓣膜性心房颤动(房颤)伴高血压患者1年后卒中发生情况,评估卒中发生的危险因素.方法 随访1年,根据研究对象是否发生卒中分为卒中组和非卒中组,应用多因素 logistic 回归模型分析卒中发生的危险因素.结果 入选495例房颤伴高血压患者,CHA2DS2-VASc≥2分466例,74例启用了抗凝治疗,抗凝治疗率14.9%,发生缺血性卒中45例,卒中发生率9.1%,多因素Logistic回归分析显示:在房颤伴高血压患者中年龄、女性、吸烟是1年缺血性卒中发生的独立危险因素,抗凝治疗是其保护因素.结论 成都地区房颤伴高血压患者1年缺血性卒中发生率较高,抗凝治疗率低,抗凝治疗能降低缺血性卒中发生,年龄、女性、吸烟是缺血性卒中发生的危险因素.
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