老年男性冠心病患者血清总胆固醇水平与其病死率的关系研究

摘要

Objective To explore serum total cholesterol(TC)levels of aged male patients with coronary heart dis-ease and its correlation with mortality. Methods From 2010 to 2013,a total of 136 aged male patients(≥65 years old)with coronary heart disease in our hospital were selected,and then divided into 4 groups according to serum TC levels:A group(n =36,TC ﹤ 4. 16 mmol/ L),B group(n = 36,TC 4. 17 - 4. 68 mmol/ L),C group(n = 35,TC 4. 69 - 5. 20 mmol/ L),D group(n = 30,TC ﹥ 5. 20 mmol/ L). Serum TG level were detected,age,BMI and mortality were recorded. Results There was no significant difference of age,BMI and serum TG levels in the four groups(P ﹥ 0. 05),while there was of serum TC lev-els and mortality(P﹤0. 05). The serum TC levels of groups A and D were higher than those of groups B and C(P﹤0. 05);mortality of all patients showed a U - like distribution;serum TC levels ﹤ 4. 16 mmol/ L or ﹥ 5. 20 mmol/ L is a risk factor of aged male patients with coronary heart disease. Conclusion Either of igher or lower serum TC levels increases the mortality of aged male patients with coronary heart disease.%目的：探讨老年男性冠心病患者血清总胆固醇水平与其病死率的关系。方法选择我院2010-2013年收治的老年（≥65岁）男性冠心病患者136例，根据血清总胆固醇水平分为4组：A 组36例，血清总胆固醇水平﹤4.16 mmol/ L；B 组35例，血清总胆固醇水平为4.17~4.68 mmol/ L；C 组35例，血清总胆固醇水平为4.69~5.20 mmol/ L；D 组30例，血清总胆固醇水平﹥5.20 mmol/ L。同时检测所有患者血清三酰甘油水平，记录其年龄、体质指数及病死情况。结果各组患者年龄、体质指数、血清三酰甘油水平比较，差异均无统计学意义（P ﹤0.05）；各组患者血清总胆固醇水平及病死率比较，差异均有统计学意义（P ﹤0.05）。A、D 组患者病死率高于 B、C 组（P ﹤0.05），所有患者病死率呈 U 型分布，血清总胆固醇水平﹤4.16 mmol/ L 或﹥5.20 mmol/ L 是男性冠心病患者病死的危险因素。结论血清总胆固醇水平过高或过低均可增加老年男性冠心病患者死亡风险。