Objective To evaluate the clinical efficacy of palliative care for elderly patients with advanced cancer . Methods Clinical data of elderly patients with advanced cancer were retrospectively analyzed .98 cases of patients with fatigue scores ≥4~10 from the Edmonton Symptom Assessment System ( ESAS) were included in the study .Patients were divided into 2 groups,50 cases received surgery and 48 cases received palliative care .Characteristics of patients ,ESAS scores and survival time were detected by chi-square test,Wilcoxon rank sum test and Kaplan-Meier.Results ESAS median pain scores in the surgery group and the palliative care group were 6 points and 4 points(P<0.001),median score of fatigue in both groups were 7 points (P=0.525),depression scores were 3 points and 2 points(P=0.004),anxiety scores were 3 points and 2 points(P<0.001), dyspnea scores were 3 points and 2 points(P<0.001),symptom distress scores were 43 points and 32 points(P<0.001).The median overall survival time in the palliative group was 17.09 months(95% CI 13.5 ~22.3 months),and that of the surgery group was 3.8 months(95%CI,3.5~4.1 months)(P<0.001).The ratio of fatigue in the palliative group was significantly low-er than that of the surgery group (P<0.05).Conclusion Comprehensive palliative care can relieve symptoms of advanced canc-er patients ,prolong survival time and improve quality of life of patients .%目的：评价姑息治疗晚期癌症老年患者的临床疗效。方法回顾性分析2012年12月至2013年12月持续接受治疗的晚期癌症患者的临床资料。疲劳评分≥4～10分的98例患者纳入本研究（由埃德蒙顿症状评估系统测定，ESAS），随机分为50例手术组患者和48例姑息组患者。患者的特点，ESAS评分和生存时间采用卡方检验、Wilcoxon秩和检验和Kaplan-Meier法检验。结果手术组和姑息组的ESAS疼痛中位分数分别为6分和4分（（P＜0．001）；疲劳中位分数都是7分（P＝0．525），抑郁症得分3分和2分（P＝0．004），焦虑得分3分和2分（P＜0．001），呼吸困难得分3分和2分（P＜0．001），症状困扰评分分别为43分和32分（P＜0．001）。总生存中位时间，姑息组是17．09个月（95％CI 13．5～22．3个月），手术组是3．8个月（95％CI，3．5～4．1个月）（P＜0．001）。姑息组患者疲劳状态比率显著低于手术组（P＜0．05）。结论全面的姑息治疗可缓解晚期肿瘤患者症状，延长患者生存时间，提高生活质量。
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