早期宫颈癌保留生育功能手术的疗效及对患者生活质量的影响

摘要

目的 探讨早期宫颈癌保留生育功能手术的疗效及对患者生活质量的影响.方法 将进行手术的65例早期宫颈癌患者按照手术方式的不同分为观察组及对照组.观察组30例患者在腹腔镜下行保留生育功能手术,对照组35例患者在腹腔镜下行子宫广泛性切除术.对2组患者围术期指标、术后并发症以及手术前后生活质量进行观察与比较.结果 2组患者围术期指标无统计学差异(P>0.05).观察组患者切除宫旁组织宽度及切除阴道长度均明显短于对照组,差异有统计学意义(P<0.05).观察组并发症发生率为23.33%,对照组为14.29%,差异无统计学意义(P>0.05).6个月随访中,2组患者均未出现复发现象.术后6个月,2组患者EORTC QLQ-30生活质量各领域得分均显著低于手术前,且观察组功能领域得分明显低于对照组,差异有统计学意义(P<0.05).结论 早期宫颈癌保留生育功能手术利于患者生活质量恢复,对于有生育要求的患者可考虑使用.%Objective To explore the clinical effect and influence to life quality of fertility preserving operation for pa-tients with early cervical cancer. Methods 65 patients with early cervical cancer were retrospectively analyzed and divided into the observation group and the control group according to different operation style. 30 patients in the observation group underwent laparoscopic fertility preserving operation,35 patients in the control group underwent laparoscopic radical hysterectomy. Then the perioperative indexes,complications and life quality were compared. Results The perioperative indexes had no great differences (P>0. 05). The cutting parametrial width and vagina length of the observation group were obviously lower than the control group (P<0. 05). Complication rate of the observation group was 23. 33%,the control group was 14. 29%. There had no differences between them (P>0. 05). There had no recurrence during 6-month follow-up. Life quality (EORTC QLQ-30) scores of the 2 groups 6 months after surgery were better than before,and the function area of the observation group was better than the control group (P<0. 05). Conclusion Fertility preserving operation for early cervical cancer patients has better life quality,could be considered for patients with fertility demand.