火焰原子吸收光谱法测定天佛参口服液及其原料药中五种金属元素

摘要

样品经硝酸和过氧化氢消化,用火焰原子吸收光谱法测定其中铜、铁、锌、钾和钠5种金属元素的含量。为克服共存组分的干扰,测定铁（Ⅲ）须在盐酸（2＋98）溶液中进行,测定锌（Ⅱ）则应在正丁醇-水（6＋94）溶液中进行,测定铜（Ⅱ）、钾（Ⅰ）及钠（Ⅰ）则在硝酸（2＋98）溶液中进行。上述各溶液的总体积均为250mL。应用此法分析了天佛参口服液及其原料药包括西洋参、天冬、佛手、土贝母、蟾酥、倒卵叶五加、沙棘果及猕猴桃根中铜、铁、锌、钾和钠5种元素的含量,用标准加入法测得其回收率在91.2%～109.0%之间,相对标准偏差（n=6）均小于3.5%。%The samples was digested with a mixed acid of HNO3 and HClO4,and contents of the 5 metal elements,Cu,Fe,Zn,K and Na,in the sample solution was determined by FAAS.To overcome the interferences of co-existing substances,iron（Ⅲ） was determined in HCl（2＋98） solution,zinc（Ⅱ） was determined in n-butyl alcohol＋H2O（6＋94） solution,and Cu（Ⅲ）,K（Ⅰ）,Na（Ⅰ） were determined in HNO3（2＋98） solution.Total volumes of all these solution were 250 mL.The proposed method was used in the analysis of samples of Tianfoshen oral liquor and its raw medicines,i.e.,american ginseng,lucid asparagus,fingered citron,bolbostemma,senso,obovatus canada,seabuckthorn and Chinese actinidia root.The values of recovery for determination of Cu,Fe,Zn,K and Na found by standard addition method were in the range of 91.2%-109.0% with values of RSD′s（n=6） less than 3.5%.