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Ⅰ期卵巢交界性肿瘤剥除术后复发危险因素分析

         

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目的:探讨年轻卵巢交界性肿瘤患者行肿物剥除术后复发的危险因素。方法回顾性分析49例行卵巢肿瘤剥除术,年龄﹤35岁,术后病理为Ⅰ期的卵巢交界性肿瘤(BOT)患者的临床及随访资料,分析术后复发的危险因素。结果随访患者中共7例复发,5年生存率为100%,无复发生存率为91.8%,不同年龄、分期、是否存在间质浸润患者术后复发情况比较,差异无统计学意义(P﹥0.05);黏液性肿瘤及微乳头型卵巢交界性肿瘤患者复发比例高于浆液性肿瘤及非微乳头型肿瘤患者,差异有统计学意义(P﹤0.05)。结论Ⅰ期BOT单侧病变患者,若术中冰冻结果为黏液性或微乳头型肿瘤,宜行患侧附件切除术;双侧病变患者,若无上述危险因素可行双侧卵巢肿物剥除术,若存在上述危险因素可行单侧附件切除术+对侧卵巢肿物剥除术。%Objective To evaluate the prognostic factors regarding recurrence after ovarian cystectomy of young pa-tients with stage I borderline ovarian tumors (BOT). Method 49 patients (age<35 years old) who underwent ovarian cystectomy with surgically confirmed stage I BOT were included in the analysis, of which the clinical and follow-up pro-files were analyzed to determine risk factors concerning postoperative recurrence. Result Of all patients, 7 had relapse, 5-year survival rate was 100%, recurrence-free survival rate was 91.8%;high risk factors for recurrence after cystectomy of BOT were mucinous tumors and micro-papillary type (both P<0.05) rather than age, stage, or stromal invasion (P>0.05). Conclusion For stage I BOT patients with unilateral lesion, and intraoperative frozen histological result shows mucinous borderline tumors or micro-papillary type, then ipsilateral oophorectomy is acceptable;for patients with bilater-al lesions while were absent of those risk factors stated above, then bilateral ovarian tumor cystectomy is feasible;other-wise, ipsilateral oophorectomy and contralateral ovarian tumor cystectomy should be considered.

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