Objective: To explore the causes of fistula failure and nursing intervention measures for hemodialysis patients .Methods: A total of 168 hemodi-alysis patients with forearm arteriovenous fistula in our hospital from January 2015 to December 2016 were selected and divided into failure group of 42 cases and success group of 126 cases according to the function of arteriovenous fistula.The reasons for arteriovenous fistula failure were analyzed with single factor analysis and logistic multi factor analysis respectively, and nursing intervention strategy was developed.Results: The differences in age, body weight, diam-eter of radial artery and cephalic vein diameter, serum protein, hemoglobin, fibrinogen, serum phosphorus, parathyroid hormone, endogenous creatinine clearance rate, incidence of diabetes, the incidence of hypertension and other aspects between the two groups were statistically significant .The logistic multi factor analysis showed that age, body mass, serum phosphorus levels, fibrinogen levels, diabetes mellitus and hypertension were risk factors for fistula fail -ure in hemodialysis patients(P <0.05).Conclusion: Advanced age, obesity, high fibrinogen, hyperphosphatemia, diabetes mellitus, hypertension and other factors are the causes of fistula failure in hemodialysis patients.%目的:探讨维持血液透析患者内瘘失败原因及护理干预措施.方法 :选取2015年1月~2016年12月在本院行前臂动静脉内瘘的维持血液透析患者168例,根据动静脉内瘘功能分为失败组42例及成功组126例,分别应用单因素及logistic多因素分析导致维持血液透析动静脉内瘘失败的原因,同时制定护理干预策略.结果 :失败组在年龄、体质量、桡动脉直径、头静脉直径、血清蛋白、血红蛋白、纤维蛋白原、血磷、甲状旁腺素、内生肌酐清除率、糖尿病发病率、高血压发病率等方面与成功组差异有统计学意义(P<0.05).经logistic多因素分析可知,年龄、体质量、血磷水平、纤维蛋白原水平、合并糖尿病、合并高血压是维持血液透析患者内瘘失败的危险因素.结论 :高龄、肥胖、高纤维蛋白原、高磷血症、合并糖尿病、合并高血压等因素是维持血液透析患者内瘘失败原因.
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