The study is aimed to explore the relationship between pulse graph characters and its blood-fat and thrombin among coronary heart disease (CHD) patients. Pathological and physiological indexes had been searched for the correlation with pulse graph parameters. Pulse detection system was applied in the collection of pulse graph among CHD patients. And pulse characters were analyzed with time domain method. Blood -fat and thrombin indexes were checked. Analytical method of canonical correlation was used in the analysis of relationship between pulse graph characters and its blood-fat and thrombin in CHD patients. The result showed that among ingredient of blood-fat, change in low-density lipoprotein (LDL) is closely related to t and t5/t4 of pulse graph in CHD. They are positive correlation. There is no obvious correlation between pulse graph characters and thrombin indexes. It is concluded that certain correlation exists between parameters of pulse graph and blood-fat indexes.%目的:探讨冠心病脉图特征与其血脂、凝血变化的关系,寻找与脉图参数可能相关的病理生理指标.方法:运用脉象检测系统采集冠心病患者的脉图,采用时域方法提取患者的脉图参数,并检测血脂、凝血四项血液指标；采用Person相关分析、典型相关分析方法等分析冠心病患者脉图参数和血脂、凝血变化的相关性.结果:血脂中低密度脂蛋白的变化与脉图参数t、t5/t4最密切相关,且呈正比关系；脉图参数与凝血四项(凝血酶原、部分活化凝血酶、INR、纤维蛋白原)无明显相关性.结论:冠心病脉图参数与血脂指标相关,提示脂质异常可能是冠心病脉图变化的物质基础之一.
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