PET-CT术前检测食管癌、非小细胞肺癌淋巴结转移的对照分析

摘要

目的:比较PET-CT术前检测食管癌(EC)、非小细胞肺癌(NSCLC)淋巴结转移的准确度,观察其诊断EC、NSCLC淋巴结转移的临床价值.方法:43例EC患者及113例NSCLC患者术前1周接受PET-CT检查,以术后病理检查结果为金标准,计算并对比术前PET-CT诊断EC、NSCLC淋巴结转移的灵敏度、特异性及准确率,分析其临床参考价值.结果:43例E C患者共切取淋巴结350枚(188组),病理诊断检出59枚淋巴结转移(16.86%),113例N S C L C患者共切取淋巴结494枚(215组),病理诊断检出131枚淋巴结转移(26.52%).术前PET-CT检测EC淋巴结转移的灵敏度、阴性预测值高于NSCLC,差异有统计学意义(P<0.05),术前PET-CT检测EC、NSCLC淋巴结转移的特异性、准确率、阳性预测值比较,差异无统计学意义(P>0.05).结论:PET-CT术前检测EC、NSCLC淋巴结转移的参考价值均较高,且评估EC淋巴结转移的灵敏度更为理想.%Objective: The objective of this study was to compare the accuracy of PET-CT on EC and NSCLC lymphatic metastasis and observe its clinical value in diagnose these lymphatic metastasis.Methods: 43 cases of EC patients and 113 NSCLC patients were examined by means of PET-CT one week before operation. The pathological results were considered as the criteria to measure the accuracy. The sensitivity, specificity and accuracy of the preoperative and postoperative PET-CT were calculated and compared.Results: Of 43 EC patients, 350 (188 groups) lymphatic gland were excised and the pathological results showed that 59 lymphatic metastasis occurred (16.86%); of 113 NSCLC patients, 494 (215 groups) lymphatic gland were excised and the pathological results showed that 131 lymphatic metastasis occurred (26.52%). The test accuracy and negative predictive value of PET-CT on EC before operation were higher than that on NSCLC, and the difference was statistically significant (P<0.05). The specificity, positive predicative value and the accuracy of PET-CT on EC and NSCLC were compared and the difference was not statistically significant (P>0.05).Conclusions: PET-CT has higher reference value in the test accuracy of EC and NSCLS lymphatic metastasis and the sensitivity on the evaluation of EC lymphatic metastasis is relatively ideal.