对比剂肾病诊断进展

摘要

The contrast - induced nephropathy( CIN )is a common reason to obtain acute renal injury,of-ten leading to short and long term renal injury, the key solution is in time diagnosis. The current clinical ap-plication of diagnosis of renal insufficiency methods such as serum creatinine, creatinine clearance rate in CIN early diagnosis has obvious limitations. Therefore, looking for early diagnosis of CIN becomes the focus of clinical research. Research shows that cystatin C, neutrophil gelatinase associated lipocalin, liver type fatty acid binding protein in CIN play an important role in the diagnosis.%对比剂肾病(CIN)是医院内获得性急性肾功能不全的常见原因,常导致短期和长期肾功能损害,而及时诊断是有效处理CIN的关键.目前临床上应用诊断肾功能不全的方法(血肌酐水平、肌酐清除率等)在CIN的早期诊断中具有明显的局限性.因此,寻找早期诊断CIN的方法成为临床研究重点.研究表明胱抑素C、中性粒细胞明胶酶相关载脂蛋白、肝脏型脂肪酸结合蛋白等在CIN的诊断中具有重要作用.