非糖尿病急性心肌梗死合并应激性高血糖患者血浆脑钠肽水平变化

摘要

Objective To explore and discuss the assessment roles of plasma brain natriuretic peptide ( BNP ) concentrations in the non-diahetic acute myocardial infarction( AMI ) patients with stress hyperglycemia. Methods Patients( 60 cases ) from January to Novemher in 2010 in our hospital with AMI were divided into two groups based on fasting plasma glucose, non-diabetic AMI with stress hyperglycemia group ( experimental group )( blood glucose≥7. 0 mmol/L ) 36 cases and AMI with normal plasma glucose(control group )( blood glucose ＜ 7.0 mmol/L ) 24 cases. The plasma BNP concentrations of all patients were measured 24 h after onset. Results Compared with control group, the BNP concentrations after 24 h were significantly increased in experimental group ( 671. 87 ± 631. 71 ) ng/L vs ( 299. 53 ±455 . 67 ) ng/L( P ＜0. 01 ). Conclusion The levels of plasma BNP concentrations can be used to determine the severity of illness in the non-diabetic AMI patients with stress hyperglycemia.%目的 探讨血浆脑钠肽(BNP)水平在非糖尿病急性心肌梗死(AMI)合并应激性高血糖患者病情评估中的作用.方法 将我院2010年1月至11月收治的AMI患者60例患者根据空腹血糖值分为两组,非糖尿病AMI合并应激性高血糖组(试验组)36例(血糖≥7.0 mmol/L),AMI未合并应激性高血糖组(对照组)24例(血糖＜7.0 mmol/L),在发病后24 h行血浆BNP浓度检测.结果 发病后24 h血浆BNP水平在非糖尿病AMI合并应激性高血糖组明显高于AMI未合并应激性高血糖组[(671.87±631.71) ng/L vs (299.53±455.67) ng/L,P＜0.01].结论 血浆BNP水平可以判断非糖尿病AMI合并应激性高血糖患者病情危重程度.