目的 探讨阻塞性睡眠呼吸暂停综合征对心血管的影响.方法 应用多导睡眠监测仪监测90例患者,根据呼吸暂停低通气指数分为两组:对照组和阻塞性睡眠呼吸暂停综合征组,分别比较两组间心律、血压的动态变化,分析阻塞性睡眠呼吸暂停综合征与心血管疾病的关系.后者再根据呼吸暂停低通气指数大小分为三组,通过比较三组间心律、血压的动态变化,分析阻塞性睡眠呼吸暂停程度对心血管疾病的影响.结果 与对照组比较,阻塞性睡眠呼吸暂停综合征患者血压升高和期前收缩发生的次数更频繁,两组间差异具有统计学意义(P<0.05);且阻塞性呼吸暂停程度越重,血压升高越明显,期前收缩次数越多.结论 阻塞性睡眠呼吸暂停综合征可能增加心血管疾病的风险.%Objective To study the effects of obstructive sleep apnea syndrome ( OSAS ) on cardiovascular diseases. Methods Polysomnography was performed on 90 subjects, who were divided into two groups on the basis of apnea hypoventilation index ( AHI ), namely, control group and OSAS group. The variations in heart rate and blood pressure were compared between the two groups to analyze the effects of OSAS on cardiovascular system. OSAS group was further divided into three subgroups based on AHI to examine the variations in heart rate and blood pressure among the three subgroups to nalyze the effects of OSAS on cardiovascular disorders. Results Compared with the control group, OSAS patients had more frequent hypertension and premature contractions ( P ＜ 0.05 ). Blood pressure and premature contraction showed an increasing trend with OSAS severity. Conclusion OSAS can increase the risks of cardiovascular diseases.
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