肺水通道蛋白的研究进展

摘要

Adjusting the water permeability of the cell membrane is the basic requirements for life main-tain. Aquaporin is a group of transporters which related to water permeability. Studies show that,aquaporin expression or function changes can rate-limiting the water transport speed. Aquaporin abnormity expressing may be related to variety of clinical forms of edema altering the water balance could treatment the diseases. Aquaporin plays an important role in maintains the balance of lung fluid in the pathogenesis of primary and secondary pulmonary edema.%调节细胞膜的水渗透性是维持生命的基本要求，水通道蛋白是细胞膜上一组与水通透性有关的转运蛋白。目前研究表明，水通道蛋白表达或功能的改变，可以改变细胞膜转运水的速度。水通道蛋白的异常表达可能与临床上各种形式的水肿形成相关，通过改变体内水的平衡可达到治疗疾病的目的。水通道蛋白在维持肺脏的液体平衡中同样起重要的作用。