血清C反应蛋白检测在小儿肺炎诊断中的价值

摘要

Objective To analyze and evaluate the serum C-reactive protein( CRP) level in diagnosis of pediatric pneumonia.Methods Total of 126 pediatric pneumonia in Maternal and Children Health Hos-pital of Ye County during Jun.2012 and Jun.2013 were selected as objects,and divided into bacterial pneumonia group(51 cases),mycoplasma pneumonia group(40 cases) and viral pneumonia group(35 cases),at the same time, 52 healthy children for physical examination were selected as control group.The white blood cell count,CRP level and positive detection rate of each group were compared and analyzed . Results The white blood cells and CRP level of bacterial pneumonia group were significantly higher than the other three groups ( P <0 .05 ) , there was no statistically significant difference between mycoplasma pneumonia group and viral pneumonia mycoplasma on white blood cell count(P >0.05),but CRP level was significantly higher than the viral pneumonia group ( P <0 .05 ) .The positive detection rate of white blood cells of bacteria pneumonia group, mycoplasma pneumonia group and viral pneumonia group had no statistically significant difference(P>0.05),CRP positive rate of bacterial pneumonia had no significant difference from mycoplasma pneumonia group(P>0.05),but they were both significantly higher than viral pneumonia group(P<0.05).Conclusion The CRP levels of different pneumonia types were different, when excluding the other CRP elevating factors,it can be used as a method for differential diagnosis of ped-iatric pneumonia types.%目的：分析并评价血清 C 反应蛋白检测在小儿肺炎分型诊断中的价值。方法选择2012年6月至2013年6月叶县妇幼保健院收治的126例小儿肺炎患儿为研究对象，根据肺炎类型分为细菌性肺炎组（51例）、支原体性肺炎组（40例）以及病毒性肺炎组（35例），同时选取同期进行健康体检的幼儿作为对照组（52例）。比较并分析各组受试者白细胞计数与 C反应蛋白水平，并按照临床诊断标准比较各组的阳性检出率。结果细菌性肺炎组患儿的白细胞及 C 反应蛋白水平均显著高于其他3组，虽然支原体肺炎组的白细胞计数与病毒性肺炎组比较差异无统计学意义（P ＞0．05），但C反应蛋白水平显著高于病毒性肺炎组（P ＜0．05）；细菌性肺炎组、支原体肺炎组以及病毒性肺炎组患儿的白细胞阳性率比较差异无统计学意义（ P＞0．05），虽然细菌性肺炎组与支原体肺炎组的C反应蛋白阳性检出率比较差异无统计学意义（P＞0．05），但均显著高于病毒性肺炎组（P＜0．05）。结论不同病原体感染的小儿肺炎血清中C反应蛋白的水平不同，在排除其他引起 C 反应蛋白升高的因素后，其可以作为鉴别诊断小儿肺炎类型的方法。