磁共振成像在肝纤维化无创性诊断和评估中的临床应用

摘要

Being an early and necessary stage in the development of liver cirrhosis ,liver fibrosis is a fun-damental pathological change of various chronic liver diseases.The diagnosis and assessment of this disease play an important role in the early clinical intervention .In spite of being the gold standard for the diagnosis and staging of liver fibrosis,liver biopsy is found to have many shortages.In recent years,magnetic resonance imaging for its non-invasiveness and easy repeatability has drawn widespread attention in the imaging diagno-sis and assessment of liver fibrosis.The specific methods include magnetic resonance elastography ,magnetic resonance diffusion weighted imaging and magnetic resonance perfusion imaging,etc.,which all have their own characteristics,A comparison between these methods is the future divection of research in this field .%肝纤维化是慢性肝病的共同病理学基础，也是发展成肝硬化的必经阶段。肝纤维化程度的诊断和评估，对该病的早期干预具有重要的临床意义。虽然肝穿刺活检现仍为肝纤维化诊断及分期的金标准，但此法具有一定的局限性。近年来，磁共振成像因其无创性和易重复性在肝纤维化的影像学诊断和评估中受到广泛重视，具体方法包括磁共振弹力成像、磁共振弥散加权成像、磁共振灌注成像等。而这些检测方法各有特点，因此对其进行筛选为未来的研究方向。