Lilium brownie is a medicinal and edible plant,which has antidepressant effect.Lily com-pound preparations have affirmative curative effect in treatment of depression.The combined usage with west-ern medicines can not only enhance curative effect but also reduce the side effects of western medicine .In recent years, pharmacological studies suggest that lily compounds can improve the behavioral changes of depression animals,increase hippocampal monoamines serotonin levels,and lower hyperfunction of hypothala-mus-pituitary-adrenal axis( HPA) .The effective ingredients of the antidepressant lily can increase serotonin and dopamine levels,reduce the adrenal cortical hormone and cortisol levels.Thorough research of lilium brownie has provided new thoughts for the development of antidepressant drugs and improve the level of diag-nosis and treatment of depression.%百合是药食同源植物，具有抗抑郁作用。百合类复方抗抑郁疗效肯定，与西药联合应用既能增强疗效还可降低西药的不良反应。百合类复方还能够改善抑郁动物的行为学变化，升高海马单胺类递质5-羟色胺水平，下调亢进的下丘脑-垂体-肾上腺（ HPA）轴功能。百合的有效成分百合皂苷也具有升高5-羟色胺、多巴胺水平，降低肾上腺皮质激素、皮质醇水平的作用。对百合进行深入研究，为开发抗抑郁新药、提高抑郁诊治水平提供了新的思路。
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