支气管肺泡灌洗液在间质性肺疾病中的应用进展

摘要

Bronchoalveolar lavage refers to repeateded lavage with sterile saline and random aspiration under electronic bronchoscope ,and collect lung lining fluid to check its cellular components and soluble substances .Because the operation is simple,safe and relatively noninvasive ,and can directly reflect local tissue pathological changes ,it has become an important means to the lung disease diagnosis and treatment has been widely used in clinical ,especially for the interstitial lung dis-ease.With the development of experimental science ,the detection of bronchoalveolar lavage fluid extends from normal cell to cell subset marker,immunology,enzymology,molecular genetics and receptor function .%支气管肺泡灌洗是指通过电子支气管镜向支气管肺泡内反复以无菌0.9﹪氯化钠注射液灌洗并随机抽吸,收集肺表面衬液,检查其细胞成分和可溶性物质.因其操作简单、较安全以及相对非创伤性,且能直接反映局部组织病理生理变化,作为研究肺科疾病的重要诊疗手段已广泛应用于临床,尤其对肺间质性疾病的诊疗和发病机制具有重要意义.随着科学的发展,支气管肺泡灌洗液的检测也从常规细胞延伸到细胞亚群标记、免疫学、酶学、分子遗传学及受体功能等方面.