D－二聚体在急性胰腺炎中的临床应用进展

摘要

Acute pancreatitis(AP) is one of common acute abdominal diseases .At present,according to AP severity and different pre-diagnosis types ,different approaches and treatment strategies are adopted in clinical .There are a lot of AP predictive indicators in clinical testing ,among which the D-dimer and other coagulation markers can indirectly reflect the status of AP in the pancreatic microcirculation , and can be used to judge AP severity and different pre-diagnosis types , understand the evolution condition and prognosis ,playing an important role in the assessment and prediction of AP .However it would be the best to be able to classify these predictors from the mechanisms of action ,which,due to the complexity of AP,still has some difficulties in practice .%急性胰腺炎（ AP）是临床常见的急腹症之一，目前临床上根据AP病情轻重及诊断预分型的不同采取不同的治疗策略及方式。在临床检验上，已有多种AP的预测指标，其中D－二聚体等凝血因子可间接反映AP时胰腺的微循环状况，通过D－二聚体等凝血功能指标可用于判断AP的病情轻重及诊断预分型，了解病情演变及预后，对AP的病情评估及预测具有重要作用。但最好能从作用机制上进行分类探讨，由于AP病因复杂，实践中还有一定困难。