目的：探讨在统一管理和检验模式下，同一所医院的3个院区主要目标菌耐药性特点是否有所不同。方法：采用SPSS19.0统计数据包，应用行×列表资料检验统计3个院区2011年主要目标菌的耐药性特点。结果：3个院区主要目标菌的耐药性有所不同：大肠埃希菌阿米卡星、环丙沙星、庆大霉素、妥布霉素、呋喃妥因、哌拉西林/他唑巴坦3个院区比较有显著性差异（P<0.05）；肺炎克雷伯菌阿米卡星、环丙沙星、头孢吡肟、妥布霉素、呋喃妥因、哌拉西林/他唑巴坦3个院区比较有显著性差异（P<0.05）；鲍曼不动杆菌3个院区所有检测抗菌药物比较均有显著性差异（P<0.05）；铜绿假单胞菌氨苄西林/舒巴坦、美罗培南、头孢他啶、妥布霉素、亚胺培南、左氧氟沙星、哌拉西林/他唑巴坦3个院区比较有显著性差异（P<0.05）；金黄色葡萄球菌苯唑西林、环丙沙星、庆大霉素、利福平、左氧氟沙星3个院区比较有显著性差异（P<0.05）。结论：在统一管理和检验模式下，同一医院不同院区其主要目标菌耐药性的发生有其本身的特点，这与新老院区在应用抗菌药物特点方面、医院感染控制方面有一定关联。%Objective:To investigate the antibiotic resistance characteristic of target bacterias in three different area of a hospital by the unified testing methods. The results will help our hospital to improve the level of rational use of antibiotics.Methods:Chi square test was used to investigate the antibiotic resistance characteristic of target bacterias in three different area of a hospital.Results:The antibiotic resistance characteristic of target bacterias was different. The characteristic of E. coli was significant different in three areas for Amikacin, Ciprofloxacin, Gentamicin, Tobramycin, Nitrofurantoin, and Piperacillin/Tazobactam (P<0.05) The characteristic of klebsiella pneumonia was significant different for Amikacin, Ciprofloxacin, Cefepime, Tobramycin, Nitrofurantoin, and Piperacillin/Tazobactam (P<0.05). The characteristic of Acinetobacter baumannii was significant different for all testing antibiotics(P<0.05). The characteristic of pseudomonas aeruginosa was significant different for Ampicillin/ Sulbactam, Meropenem, Ceftazidime, Tobramycin, Imipenem, Levofloxacin, Piperacillin/ Tazobactam (P<0.05), and staphylococcus aureus was significant different for Oxacillin, Ciprofloxacin, Gentamicin, Rifampicin, Levofloxacin (P<0.05).Conclusions:Because of the difference of antibiotics application and hospital infection control in different area of a hospital,we found that the antibiotic resistance characteristic of target bacteria was different.
展开▼
