扩散加权成像的表观扩散系数对急性后循环梗死的应用价值

摘要

Objective To explore the applied value of apparent diffusion coefficient (ADC) of diffusion weighted image (DWI) in acute posterior circulation infarction.Methods 44 patients with posterior circulation infarction were studied, which included 15 cases of occipital lobe infarction on one side, 11cases of cerebellum infarction on one side and 18 cases of brain stem infarction and were rechecked with DWI within one week after disease attack.Results Within one week after attack, the ADC of core and borderline of occipital lobe infarction and cerebellum infarction on one side decreased respectively and had significant difference from that of the other side of infarct (P＜0.01).The ADC of core of brain stem infarction decreased and had significant difference from that of infarct borderline (P＜0.05).2 weeks after infarct, the ADC of infarct core decreased and had significant difference from that of infarct borderline and other side of infarct (P＜0.05), but the ADC of infarct borderline had no significant difference from that of the other side of infarct (P ＞0.05).There were high signal realm of DWI deflated in 8 eases with occipital lobe infarction, 6 cases with cerebellum infarction and 13 cases with brain stem infarction.Conclusions ADC is a method to evaluate cerebral ischemia and quantitative analysis of ADC can help assess ischemic degree.%目的 探讨扩散加权成像(DWI)之表现扩散系数(ADC)对急性后循环梗死的应用价值.方法 对44例发病一周以内行临床及磁共振DWI检查确诊为急性后循环梗死的患者,于二周后复查磁共振DWI检查.结果 发病一周内,一侧枕叶和一侧小脑梗死的核心、梗死的边缘和其对侧镜像区ADC值比较,其差异均有统计学意义(P<0.01).脑干梗死的核心ADC值和其梗死边缘比较,差异有统计学意义(P<0.05).二用后复查DWI检查,梗死的核心ADC值和其边缘及镜像区差异有统计学意义(P<0.05).而梗死的边缘和镜像区差异无统计学意义(P>0.05),且一侧枕叶梗死者有8例DWI高信号范围较前缩小,小脑梗死者有6例DWI高信号范围较前缩小,脑干梗死者有13例DWI高信号范围较前缩小,结论 ADC值是一种客观的评价脑缺血的方法,其定量分析有助于判断缺血的程度及恢复情况.