外周动静脉双管同步换血在新生儿高胆红素血症中的临床应用

摘要

目的 探讨治疗新生儿高胆红素血症的换血方法.方法 采用外周动静脉双管同步换血(输入和输出均由容量泵控制同步进行)治疗新生儿高胆红素血症.结果 换血后15例新生儿高胆红素血症患儿,总胆红素由(470.45±32.43)mmol/L降至(250.37±16.50) mmol/L,间接胆红素由(378.78±20.54)mmol/L降至(182.74±19.18) mmol/L,治疗前后比较,差异显著(均P＜0.01)；15例高胆红素血症患儿均病情好转.结论 外围动静脉双药同步换血是清出患儿体内毒素的有效方法,且操作方便,安全性高.我们认为,做好术前准备,术中密切观察生命体征,保证输入与输出血量的动态平衡等是该疗法的关键,可在临床推广应用.%Objective To discuss the treatment method of exchange transfusion in neonates with hyperbilirubinemia. Methods 15 neonatal with hyperbilirubinemia was treated with double input and output by the capacity of pump control synchronization. Results The total bilirubin decrease form (470. 45 ± 32. 43) mmol / L to (250. 37 ± 16. 50) mmol / L, indirect bilirubin from (378. 78±20. 54) mmol / L To (182. 74±19. 18) mmol / L after treatment. 15 cases were in better condition. Conclusion It is effective to treat neonates with hyperbilirubinemia with double input and output by the capacity of pump control synchronization.