目的 观察Ⅱ型糖尿病伴原发性高血压患者窦性心率震荡变化并探讨其临床意义.方法 对行24小时动态心电图检查患者的心电图资料进行分析,其中Ⅱ型糖尿病患者45例,单纯性原发性高血压病45例,Ⅱ型糖尿病伴原发性高血压病者40例,健康对照者45例,均检出有室性早搏,并计算TO及TS等指标.结果 Ⅱ型糖尿病伴原发性高血压病组TO较健康对照组高,TS较对照组低(P＜0.05)；与Ⅱ型糖尿病组或单纯原发性高血压病组比较,差异有统计学意义(P＜0.05).结论 Ⅱ型糖尿病伴原发性高血压病患者窦性心率震荡现象明显减弱,自主神经受损,易发生恶性心脏事件.%Objective To observe the sinus rhythm turbulence of patients with primary hypertension and type 2 diabetes and explore the clinical significance. Methods Patients checked by 24h dynamic electrocardiogram were chosen from 2008 to 2011 in our hospital, including simple primary hypertension(45 cases), type 2 diabetes (45 cases), primary hypertension and type 2 diabetes (45 cases) and healthy controls (45 cases). All the cases were detected ventricular ex-trasystoles and calculated TO and TS index. Results The TO indexes of primary hypertension and type 2 diabetes group were higher than that of the healthy controls group and the TS index was lower than that of the latter(P＜0. 05). The differences were statistically significant between primary hypertension and type 2 diabetes group and type 2 diabetes group or simple primary hypertension group(P＜0. 05). Conclusion Sinus rhythm turbulence of patients with primary hypertension and type 2 diabetes is weakens obviously and autonomic nerve is damaged. Patients are more prone to malignant cardiac events.
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