基于指端容积血流脉动波形特征的量化分析在新兵应激反应评估中的应用

摘要

目的 探讨采用指端容积血流脉动波形(PPG-)描记信号量化分析技术评估新兵应激状态的可行性.方法 分层随机抽取58名新兵作为测试对象,采用HC2180-D指夹式无创血流参数检测系统的增强型解决方案,以负性情绪图片作为刺激材料,从被试者经图片刺激前后的PPG描记信号中提取特征参数作为量化和比较研究的生物信息,以简明心境量表测试作为效标,记录相关试验数据.结果 作为从PPG信号中提取的特征参数和生物学标记,回缩充盈分数(CDF)与血管回缩期面积重心纵坐标(Y2)值在被试受到负性情绪图片刺激后明显升高(P＜0.05),而中性图片刺激后产生的变化无统计学意义( P＞0.05) ;CDF、Y2均与简明心境量表中的紧张、抑郁、愤怒呈中度正相关(P＜0.05),与疲乏、迷惑呈低度正相关(P＜0.05),与活力呈中度负相关(P＜0.05).结论从指端采集的脉动波形图中提取的特征参数和生物学标记具有很高的敏感性和可操作性,可用于新兵应激状态的量化评估.%Objective To investigate the feasibility of stress assessment based on specific quantification techniques and analysis of stress status with photoplethysmographic (PPG) signals. Methods The PPG signals were stratified and randomly sampled from 58 recruits before and after stress induced by International Affective Pictures Systems (LAPS) images of negative emotion. The signals were collected and processed in a tool called HC2180-D, an enhanced solution of a blood flow monitoring system, through which the characteristic parameters of pulsatile waveform were derived as components of bioinformation for quantitative and comparative study. A concise mental rating scale, the "brief profile of mood state" (BPOMS), was used as criterion. Results As the characteristic parameter and biomarker were derived, significant increases in values were observed in both the vasoconstriction/vasodilation fraction (CDF) and the ordinate of the area under the pulse contour of the vasoconstriction phase (Y2) when the recruits were shown LAPS images of negative emotion ( P<0.05),compared with the resulting values when I APS images of neutral emotion (P>0.05) were shown. The values of both the CDF and the Y2 were positively correlated in mid-range to tension, depression, and anger (P<0.05), and in low-range to fatigue and confusion ( P<0.05). The values were negatively correlated in mid-range with vigor ( P<0.05). Conclusion The characteristic parameter and biomarker derived from the pulsatile waveform obtained at the fingertip are highly sensitive and can be utilized as measures in the quantitative assessment of stress response among recruits.