目的：探讨高原施工人员不同海拔高度、不同居住时间氧疗前后微循环的变化。方法选取2000名高原施工人员，在不同海拔，监测并分析3、7、15、30、60、90 d、1年吸氧前后微循环变化。结果吸氧组微循环血流、血管形态、红细胞聚集、管襻形态、襻顶淤血、襻周出血、乳头下血管丛等变化明显优于不吸氧组。吸氧前血液流态积分显著降低，前后比较差异有统计学意义（χ2＝6．48，P＜0．05），管周状态差异有统计学意义（χ2＝4．36，P＜0．05），积分显著增高，差异有统计学意义（P＜0．05），海拔5000 m以上吸氧后较吸氧前管周状态积分增高非常显著（P＜0．01）。其他积分和总积分虽有增高或降低，均无统计学意义。结论微循环变化明显好于对照组，尤其是血管清晰度、血液流态流速、血管变异、红细胞聚集等方面。%Objective To study the change of microcirculation in construction personnel residing on different altitude and for different time before and after oxygen therapy .Methods Microcirculation changes in 2 000 plateau construction personnel in different altitude, 3, 7, 15, 30, 60, 90 d, 1 y before and after oxygen therapy were observed .Results In oxygen groups, microcirculation blood flow, blood vessels, erythrocyte aggregation, tube loop, loop congestion, loop bleeding, vascular plexus under nipple, were bet-ter than in no oxygen groups .blood flow integral was significantly reduced before oxygen , comparison before and after was sigmticantlg different (χ2 =6.48, P<0.05), comparison of pipe weeks state both showed significant difference (χ2 =4.36, P<0.05), scores were significantly higher (P<0.05) at an altitude of more than 5 000, oxygen status before the oxygen tube weeks after integral in-creased significantly (P <0.01).Other integral and total integral was higher or lower , without statistically significant difference . Conclusions Microcirculation changes are much better than those in groups without oxygen , especially the clarity of blood vessels , the blood flow velocity variation, erythrocyte aggregation, blood vessels, etc.
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