血清PCT和CRP联合检测在儿科感染中的临床价值

摘要

目的：探讨血清PCT和CRP联合检测在儿科感染中的临床价值。方法：应用免疫荧光定量法和乳胶免疫比浊法分别检测172例儿科感染患者及78例正常体检儿童血清PCT和CRP水平。结果：细菌感染组PCT及其阳性率明显高于非细菌感染组和正常对照组（P<0.05），而非细菌感染组和正常对照组的PCT及其阳性率无明显差异；细菌感染组和非细菌感染组CRP及其阳性率比较差异均无统计学意义（P>0.05），但均高于正常对照组，且差异具有统计学意义（P<0.05）。结论：联合检测感染患儿的血清PCT和CRP，具有敏感度及特异度高的特点，有助于感染疾病的鉴别诊断及预后判断，对指导合理应用抗菌素有其重要的临床意义。%Objective:To explore clinical value of serum Procalcitonin(PCT)combine C-reactive protein(CRP)detection in pediatric infections. Method:Serum PCT and CRP levels of 172 pediatric infection patients and 78 normal children were detected by Immunofluorescence quantitative method and latex turbidimetric immunoassay respectively. Result:PCT and its positive rate of bacterial infection group was obviously higher than that of the bacterial infection group and normal control group(P<0.05),the bacterial infection group and normal control group of PCT and its positive rate comparative had no difference;Bacterial infection group and the CRP and its positive rate to compare differences between the bacterial infection group were no statistical significance(P>0.05),but were higher than in normal control group,and the difference is statistically significant(P<0.05). Conclusion:Serum PCT combine CRP detected has the characteristics of high sensitivity and specificity,contribute to differential diagnosis and prognosis,guide reasonable usage of antibiotics to pediatric infection.