目的：探讨荧光支气管镜在肺癌早期诊断中临床意义。方法：选取符合入选标准的患者160例，随机分为白光电子支气管镜组（WLB组）和自发性荧光支气管镜组（AFB组），检查获取病理和留取冲洗液，统计肺癌诊断数据，对两组确诊肺癌患者检出情况及两组中镜下异常表现进行分析。结果：AFB组中肺癌检出率60.42%，WLB组中肺癌检出率45.31%，AFB组肺癌检出率明显高于WLB组（P<0.01）。AFB组镜下异常表现阳性率90.50%，WLB组阳性率64.30%，AFB组镜下异常表现阳性率明显高于WLB组（P<0.01）。结论：AFB检查确诊肺癌明显优于WLB尤其对肺癌早期诊断。%Objective:To investigate the clinical significance of autofluorescence bronchoscopy(AFB)in the early diagnosis of lung cancer. Method:160 patients were randomly divided into white light bronchoscopy group(WLB group)and autofluorescence bronchoscopy group(AFB group), and all suspicious findings were recorded for biopsy specimens and bronchoalveolar lavage fluid,and all statistical data of lung cancer patients and endoscopic abnormal detections were analyzed in two groups.Result:The diagnostic rate of lung cancer was 60.42%in AFB group,the diagnostic rate of lung cancer was 45.31%in WLB group,the diagnostic rate of AFB group was significantly higher than WLB group(P<0.01).The AFB group,the positive rate of endoscopic abnormal detection was 90.50%,the WLB group,the positive rate of 64.30%,the positive rate of AFB group was significantly higher than the WLB group(P<0.01).Conclusion:AFB is significantly superior to WLB especially for early diagnosis of lung cancer.
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