奥美拉唑与抗生素联合治疗30例慢性胃炎的疗效及其安全性

摘要

Objective:To investigate the efficacy and safety of omeprazole and antibiotics in treatment of chronic gastritis.Method:A total of 60 cases,of chronic gastritis patients were selected and they were randomly divided into control group(n=30)and observation group(n=30).Control group was given clarithromycin therapy,while observation group was given omeprazole and clarithromycin therapy.Clinical symptoms,overall treatment efficiency and the rate of adverse reactions in the two groups were compared.Result:The total efficiency of observation group was 96.67%,while control group was 73.33%,there was a significant different between the two group(P<0.05).The adverse reaction rate of two groups had no significant difference(P>0.05).Conclusion:Omeprazole and clarithromycin is effective with less adverse reaction,and is worthy of promoting.%目的：探讨奥美拉唑和抗生素联合治疗慢性胃炎的疗效及其安全性。方法：60例慢性胃炎的患者随机分为对照组（n=30）和观察组（n=30）。给予对照组单独口服克拉霉素治疗，给予观察组奥美拉唑和克拉霉素联合治疗，对比两组的临床症状改善情况、治疗效果及不良反应发生情况。结果：治疗后，观察组的治疗总有效率为96.67%，对照组的治疗总有效率为73.33%，两组比较差异有统计学意义（P<0.05）；观察组出现的不良反应率和对照组相比，差异无统计学意义（P>0.05）。结论：奥美拉唑和克拉霉素联合治疗的效果确切，不良反应少，值得推广。