重复经颅磁刺激对血管性认知障碍非痴呆型的疗效观察

摘要

Objective:To investigate the effect of repetitive transcranial magnetic stimulation(rTMS)on the vascular cognitive impairment-no dementia.Method:62 vascular cognitive impairment-no dementia patients from January 2011 to September 2012 in our hospital were randomly assigned to the real rTMS group,sham rTMS group and control group.Funtion was evaluated by using Montreal cognitive assessmentand(Montreal cognitive assessment,MoCA)and clock drawing test(clock drawing test,CDT)before and after 10-days treatment of the rTMS.Result:For all the patient in the groups the MoCA,CDT showed differences after medical treatment(P<0.05).Compared with the other two groups,the real rTMS group showed better efficacy(P<0.05);there was no difference between sham rTMS group and control group.Conclusion:rTMS has therapeutic effect for the patients of vascular cognitive impairment-no dementia.%目的：讨论重复经颅磁刺激（rTMS）治疗非痴呆型血管性认知障碍的疗效。方法：收集本院2011年1月-2012年9月的非痴呆型血管性认知障碍的62例患者，并随机分为对照组、rTMS真磁刺激组和rTMS假磁刺激组，进行10 d治疗。应用蒙特利尔认知测评量表（MoCA）和画钟试验（CDT）进行认知功能的评价。结果：药物治疗后各组MoCA、CDT评分较治疗前均有明显升高（P<0.05），治疗后rTMS真刺激组与另两组比较差异均有统计学意义（P<0.05），假磁刺激组与对照组比较差异无统计学意义（P>0.05）。结论：rTMS对非痴呆型血管性认知障碍患者有治疗作用。