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Method for identifying and treating patients who may benefit from treatment of dementia, cerebrovascular dementia, Parkinson dementia, Alzheimer's disease and / or mild cognitive impairment using omega-3 fatty acids

机译:使用omega-3脂肪酸鉴定和治疗可能受益于痴呆症,脑血管性痴呆,帕金森氏痴呆,阿尔茨海默氏病和/或轻度认知障碍的患者的方法

摘要

A method of identifying a patient likely to benefit from omega-3 fatty acid therapy for dementia, vascular dementia, Parkinson's dementia, Alzheimer's disease, and/or mild cognitive impairment includes identifying a patient having abnormal brain activity by conducting one or more baseline scans of the patient's brain, administering a first dosage regimen of omega-3 fatty acids to the patient so identified, thereafter conducting one or more assessment scans of the patient's brain, comparing the one or more assessment scans with the one or more baseline scans to determine any improvement in the patient's brain activity, and selecting any patient having an improvement in brain activity to receive omega-3 fatty acid therapy for the treatment or prevention of dementia, vascular dementia, Parkinson's dementia, Alzheimer's disease, and/or mild cognitive impairment. Another method of of identifying a patient likely to benefit from omega-3 fatty acid therapy for a brain disorder includes the steps of conducting a basal metabolic scan of the patient's brain, thereafter administering a stimulated perfusion dose of omega-3 fatty acids to the patient, conducting a stimulated perfusion scan of the patient's brain, and comparing the basal metabolic scan with the stimulated perfusion scan to differentially diagnose a brain disorder that is treatable with omega-3 fatty acids. Further included are methods of treating a patient identified as being likely to benefit from omega-3 fatty acid therapy, and diagnostic tests to identify such patients.
机译:一种识别可能从omega-3脂肪酸疗法中受益的痴呆症,血管性痴呆,帕金森氏痴呆症,阿尔茨海默氏病和/或轻度认知障碍患者的方法包括通过对患者进行一次或多次基线扫描来确定其大脑活动异常的患者患者的大脑,对如此确定的患者施予第一剂omega-3脂肪酸治疗方案,然后对患者的大脑进行一次或多次评估扫描,将一次或多次评估扫描与一次或多次基线扫描进行比较,以确定是否存在任何改善患者的大脑活动,并选择任何大脑活动得到改善的患者接受omega-3脂肪酸疗法来治疗或预防痴呆,血管性痴呆,帕金森氏痴呆,阿尔茨海默氏病和/或轻度认知障碍。识别可能会从omega-3脂肪酸疗法中获益的患者的另一种方法包括对患者大脑进行基础代谢扫描的步骤,然后向该患者给药刺激的灌注剂量的omega-3脂肪酸,对患者的大脑进行刺激性灌注扫描,并将基础代谢扫描与刺激性灌注扫描进行比较,以鉴别诊断可使用omega-3脂肪酸治疗的脑部疾病。还包括治疗被鉴定为可能受益于omega-3脂肪酸治疗的患者的方法,以及用于鉴定此类患者的诊断测试。

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