130例非酒精性脂肪肝患者临床分析

摘要

目的：了解非酒精性脂肪肝患者的临床特点。方法：分析130例非酒精性脂肪肝（NAFLD组）患者和50例健康对照者（对照组）的临床资料，包括身高、年龄、性别、体质量、腰围、血压、空腹血糖（FPG）、甘油三酯（TG）、总胆固醇（TC）、谷丙转氨酶（ALT）、尿酸（UA）、高密度脂蛋白（HDL-C）及低密度脂蛋白（LDL-C）等。结果：NAFLD患者高发年龄在40~60岁之间，女性随年龄增长发病率逐渐升高。NAFLD患者体质量、体质量指数、腰围、血压、FPG、TG、LDL-C、ALT、UA水平均明显高于对照组，而HDL-C水平明显低于对照组，差异均有统计学意义（P<0.05）。结论：及早进行临床生化和超声检查，同时改变不良生活方式，可以有效预防NAFLD的发生发展。%Objective:To analyze the clinical characteristics of NAFLD.Method:The clinical data of 130 cases of nonalcoholic fatty liver disease(NAFLD group)and 50 cases of normal persons(control group)were analyzed, including height,age,sex,weight,body mass index(BMI),waistline,blood pressure,fasting blood glucose(FPG), triglycerides(TG),cholesterol(TC),Amino-transferase(ALT),uric acid(UA),low-density lipoprotein(LDL-C), high density lipoprotein(HDL-C).Result:NAFLD in patients with high-risk aged 40-60 years old,women growth rates increased with age.The weight,BMI,waistline,blood pressure,FPG,TG,LDL-C,ALT and UA in the NAFLD group were significantly higher than those in the control group,but HDL-C level was significantly lower than the control group,the differences were statistically significant(P<0.05).Conclusion:Early clinical biochemical and ultrasonic examination and the change of lifestyle can effectively prevent the development of the NAFLD.