胎儿内脏异位综合征的产前超声诊断及临床分析

摘要

Objective:To investigate the prenatal ultrasonic features and clinical value of in diagnosis of fetal heterotaxy syndromes.Method:23 fetuses with heterotaxy syndromes confirmed by prenatal ultrasound were analyzed retrospectively.Compared pathologic autopsy after induced labor,summarized and analyzed its prenatal ultrasonographic characteristics.Result:Of 23 fetuses with heterotaxy syndromes,16 fetuses had right isomerism with complex cardiac anomalies,15 fetuses with asplenia,1 fetus with spleen dysplasia;7 fetuses had left isomerism with interruption of inferior vena cava with azygos continuation,4 fetuses with complex cardiac anomalies,3 fetuses with normal cardiac structure,3 fetuses with atrioventricular block.Conclusion:Prenatal ultrasound in diagnosis of heterotaxy syndromes is feasible,in favour of the prenatal counseling and clinical treatment.%目的：探讨胎儿内脏异位综合征的产前超声特征及临床价值。方法：对产前超声诊断内脏异位综合征的23例胎儿进行回顾性分析，对照引产后病理解剖所见，对其产前超声特征进行总结分析。结果：23例内脏异位综合征胎儿中，16例右侧异构综合征，7例左侧异构综合征，16例右侧异构综合征胎儿均表现复杂心脏畸形，15例无脾，1例脾发育不良；7例左侧异构综合征胎儿均表现下腔静脉离断、奇静脉或半奇静脉扩张，其中4例合并复杂心脏畸形，3例心脏结构正常，3例合并房室传导阻滞。结论：产前超声是诊断胎儿内脏异位综合征有效可行的方法，有利于产前咨询及预后评估。