Objective:To investigate the clinical value of endocrine disorders of infertility by combination therapy. Method: 110 patients with infertility of endocrine disorders in our hospital were selected as the research objects from June 2013 to June 2014,all the patients were treated by human menopausal gonadotropin, chorionic gonadotropin and crow clomiphene combined treatment, and the treatment effect was analysed.Result:110 patients were treated with 233 cycles, 203 cycles had ovulation, the ovulation rate was 87.1%(203/233).110 patients were treated with the first cycle of 36 cases success, 74 patients were treated with the second cycle of 25 cases success, 49 patients were treated with the third cycle of 7 cases success. 68 cases were successful,the pregnancy rate was 61.8%(68/110);6 patients occurred ovarian hyperstimulation syndrome, accounted for 5.5%(6/110).Conclusion: Using human menopausal gonadotropin, human chorionic gonadotropin and combined medication of clomiphene citrate three drug way on endocrine disorders of patients with infertility treatment has good effect,it is conducive to the promotion of ovulation and pregnancy,has less adverse reaction, significant clinical value, so it is should be popularized and applied.%目的：探讨内分泌失调性不孕症采用联合用药治疗的临床价值。方法：选取2013年6月-2014年6月在本院就诊的110例内分泌失调性不孕症患者作为本次研究的研究对象，收集的110例内分泌失调性不孕症患者均展开人绝经促性腺激素、绒毛膜促性腺素及克罗米芬联合治疗，并对其治疗效果进行分析总结。结果：本组110例患者共进行233周期的治疗，其中203周期有排卵现象，其排卵率为87.1%（203/233）。110例患者均进行第1周期治疗，成功妊娠36例；74例患者进行第2周期治疗，成功妊娠25例；49例患者进行第3周期治疗，成功妊娠7例，本组110例患者中共68例患者成功妊娠，其妊娠率为61.8%（68/110）。本组110患者中仅6例患者发生卵巢过度刺激综合征，占5.5%（6/110）。结论：采用人绝经促性腺激素、绒毛膜促性腺素及克罗米芬三种药物联合用药的方式对内分泌失调性不孕症患者进行治疗可取得较好的效果，有利于促进患者排卵及妊娠，且不良反应少，临床价值显著，应推广应用。
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