雾化吸入布地奈德联用孟鲁斯特治疗小儿咳嗽变异性哮喘的疗效观察

摘要

Objective:To investigate and analyze the clinical effect of budesonide combined with montelukast in treatment of children with cough variant asthma.Method:60 cases of infantile cough variant asthma from April 1, 2013 to April 30,2014 in our hospital were selected,according to the treatment methods they were divided into test group(30 cases)and control group(30 cases).Control group patients were given budesonide treatment,experimental group patients were given oral montelukast on the basis of the control group,their therapeutic effect were observed. Result:The treatment efficiency of test group(96.67%)was higher than that in the control group(73.33%),the test group the recurrence rate(6.67%)was lower than that of the control group(20.00%),after treatment,relieve cough time, cough disappeared time of the test group were significantly better than the control group(P<0.05).Conclusion:Budesonide combined with oral montelukast has good clinical effect on treating children with cough variant asthma,they improve the treatment efficiency and the patients’ PEF,FEV1,FVC,FEV1/FVC and a number of items of pulmonary function, clinical can consider expanding application.%目的：探讨分析布地奈德联用孟鲁斯特治疗小儿咳嗽变异性哮喘的临床效果。方法：选取2013年4月1日-2014年4月30日本院60例小儿咳嗽变异性哮喘患者，根据治疗方式分为试验组（30例）和对照组（30例）。给予对照组患者布地奈德混悬液雾化治疗，在对照组的基础上，给予试验组患者口服孟鲁斯特联合治疗，观察两组患者的治疗效果。结果：试验组的治疗有效率（96.67％）高于对照组（73.33％），试验组的复发率（6.67％）低于对照组（20.00％），治疗后，试验组患者的咳嗽减轻时间、咳嗽消失时间、咳嗽哮喘发作减少次数均显著优于对照组，差异均具有统计学意义（P<0.05）。结论：布地奈德混悬液雾化与孟鲁斯特口服联用治疗小儿咳嗽变异性哮喘的临床效果好，提升治疗有效率，可考虑扩大应用。