幸福感提升训练对精神分裂症患者认知功能和社会功能的影响

摘要

Objective:To investigate the influence of increase of happiness training on cognition function and social function in patients with schizophrenia.Method:According to classification and diagnostic criteria of mental disorders,Third Edition China(CCMD-3)in 84 patients withschizophrenia diagnostic criteria,were randomly divided into two groups. Study group received well-being enhancement training combined with quetiapine in treatment,control group received single Yongkuiquetiapine,the positive and negative syndrome scalePANSS,Wisconsin Card Sorting Test WCST and continuous operation test to evaluate the curative effect of CPT.Result:After 12 week study group PANSS total,positive factor,negative factor score and WCST and CPT in W1,W2,C1,C2 compared with those before treatment were significantly different,and the treatment for 12 weeks with PANSS total scores and positive factor,had more negative factor score and W1,W2,C1,C2 and control group very significant difference.Conclusion:The increase in happiness of training not only can improve the clinical efficacy in patients with schizophrenia,and the schizophrenia cognitive function and social function of patients also has the distinct improvement.%目的：探讨幸福感提升训练对精神分裂症患者认知功能和社会功能的影响。方法：将符合中国精神障碍分类与诊断标准第3版（CCMD-3）精神分裂症诊断标准的患者84例，随机分为两组。研究组给予幸福感提升训练合并喹硫平治疗，对照组单用喹硫平治疗，以阴性和阳性症状量表PANSS，威斯康星卡片分类测验WCST和持续操作测验CPT评定疗效。结果：治疗12周末研究组PANSS总分，阳性因子分、阴性因子分及WCST和CPT中W1、W2、C1、C2较治疗前有显著差异，并且治疗12周末PANSS总分及阳性因子分、阴性因子分及W1、W2、C1、C2与对照组比较差异均有统计学意义。结论：幸福感提升训练不仅能提高精神分裂症患者的临床疗效，而且对精神分裂症患者的认知功能和社会功能也有较明显的改善。