急性脑卒中后抑郁状态的临床分析

摘要

Objective:To study the relationship among the state of post stroke depression,the degree of neurological impairment and the responsible lesion site.Method:160 patients with acute cerebral stroke were tested and the degrees of neurological impairment and were graded by introducing Hamilton Depression Rating Scale.35 patients were found with post stroke depressive state.Statistic analysis was done under conditions of different relative factors.Result:The total incidence of post stroke depression was 21.9%,which was positively correlated to the degree of neurological impairment significantly.The left hemisphere lesions were prone to depression than the right ones.The basal ganglia injuries were prone to depression.Conclusion:The severe neurological dysfunction can promote the occurrence of depression,and the occurrence of post stroke depression is associated with the responsible lesion site.%目的：了解脑卒中后抑郁状态与神经功能缺损程度、责任病灶部位的关系。方法：采用Hamilton抑郁量表对160例急性脑卒中患者进行测试检查及神经功能缺损程度评分，其中合并脑卒中后抑郁状态35例，在不同的相关因素条件下进行统计学分析。结果：脑卒中后抑郁状态的总发生率21.9%，其发生率与神经功能缺损程度呈显著正相关；左半球病灶者较右半球病灶者易发生抑郁状态；基底节区损伤易发生抑郁状态。结论：严重的神经功能障碍能促进抑郁状态的发生，脑卒中后抑郁状态的发生与责任病灶部位有关。