The Clinical Analysis on Acute Oral Cavity Mucositis Caused by the Radiotherapy for the Head and Neck Cancer

摘要

Objective: To observe and discuss the clinical effect of the treatment of the reduced glutathione injection acute oral cavity mucositis caused by radiotherapy for head and neck cancer. Methods: We select from August 2012 to August 2014 78 cases of the head and neck radiotherapy of head and neck cancer patients, both by pathology diagnosed with head and neck malignant tumours. The patients were randomly divided into treatment group and control group, two groups of the dose of radiation technology and basic consistent. The treatment group is used when patients mucositis II level, intravenous drip, and the reduced glutathione injection was given until the end of radiotherapy. The control group when patients mucositis II level, began to give intravenous drip 0.9% saline until the end of radiotherapy. Results: For the treatment of oral cavity mucous membrane inflammation, two groups of patients with oral cavity mucositis evaluation result comparison, are no obvious difference, there is no statistical significance (P >0.05). After radiotherapy, the inflammation of the oral mucosa in patients with two groups of case investigation and comparison results show that the evaluation results of patients with oral mucositis treatment group was obviously better than the control group, the significant difference was statistically significant (P < 0.05). Conclusion: The reduced glutathione injection for treating head and neck radiotherapy caused by acute inflammation of the oral mucosa has the certain effect, and it is worthy of clinical using.