三种不同检查方法对早产儿脑损伤评估优越性比较

摘要

Objective: To explore and analyze the integration of electroencephalogram (EEG) amplitude, CDI, MRI in the diagnosis of premature infant brain injury research, aiming at a premature infant brain injury to provide reliable clinical diagnosis.Method:120 premature infants treated in our hospital of pediatrics from August 2012 to August 2012 were selected, they were all tested by EEG, CDI,and MRI, and the test results were recorded.Result:the amplitude of integration of EEG examination results: this group of premature infants with 48 cases formed discontinuous low voltage or pathological type graphics, positive rate was 40.00%( 48/120), and failed to detect the mature CY. CDI examination results: this group of 33 cases of patients with intracranial found positive lesions, positive rate was 27.50%( 33/120), including 15 cases of premature infants diagnosed with intraventricular hemorrhage, accounted for 45.45%( 15/33), and 18 cases of premature infants diagnosed with hypoxia ischemic change, accounted for 54.55%( 18/33). MRI results: the group with 62 cases in preterm infants found positive in intracranial lesions, whose rate was 51.67%( 62/120), including 34 cases diagnosed with the brain ischemia, 19 cases diagnosed parenchymal dotted hemorrhage, accounted for 30.66%(19/62), 9 cases diagnosed with the brain ischemia combined subarachnoid hemorrhage, accounted for 14.52%( 9/62). Conclusion:The accuracy and sensitivity of MRI diagnosis for premature infants is obviously higher than that of amplitude integration of electroencephalogram( EEG) and CDI. electroencephalogram( EEG) to the integration of these amplitude can be premature abnormal changes of sleep-wake cycle for diagnosis, and served as first diagnosis and follow-up tracking method applied in the clinical work.%目的：探究与分析振幅整合脑电图、彩超、MRI在早产儿脑损伤中的诊断研究，旨在为早产儿的临床脑损伤提供可靠的诊断依据。方法：选取2012年8月-2014年8月本院儿科收治的120例早产儿，在其住院期间给予振幅整合脑电图、彩超、MRI检查，观察与记录三种方法的检测结果。结果：振幅整合脑电图检查结果：早产儿中有48例表现为不连续低电压或病理型图形，阳性率为40.00%（48/120），且未能检测到成熟CY。彩超检查结果：早产儿中有33例颅内发现阳性病灶，阳性率为27.50%（33/120），其中15例早产儿被诊断为脑室内出血，占45.45%（15/33），另有18例早产儿被诊断为缺氧缺血性改变，占54.55%（18/33）。MRI检查结果：早产儿中有62例在颅内发现了阳性病灶，阳性率为51.67%（62/120），其中有34例诊断为脑室内缺血，19例诊断为脑实质点状出血，占30.66%（19/62），9例诊断为脑室内缺血合并蛛网膜下腔出血，占14.52%（9/62）。结论：MRI对于早产儿诊断的准确性及敏感性明显高于振幅整合脑电图及彩超检查，其中振幅整合脑电图可通过针对早产儿醒睡周期异常改变进行诊断，而彩超则可作为初诊及随访追踪的方法推广应用于临床工作中。