目的：观察家庭督导化疗管理对初治涂阳肺结核患者服药依从性的影响，并分析其临床效果。方法：300例初治涂阳肺结核患者随机分为两组组，每组各150例，常规管理组采用常规管理，家庭督导化疗管理组在常规管理基础上实施家庭督导化疗管理。比较两组患者服药依从率及治愈率。结果：家庭督导化疗管理组患者服药依从率明显高于常规管理组，两组比较差异有统计学意义（χ2=9.549，P<0.05）；家庭督导化疗管理组患者治愈率明显高于常规管理组，两组比较差异有统计学意义（χ2=9.959，P<0.05）。结论：家庭督导化疗管理可明显提高初治涂阳肺结核患者服药依从性和治愈率，从而减少耐药结核杆菌的产生，有效促进肺结核患者迅速康复。%Objective: To observe the influence on the medication adherence of family steering chemotherapy management for the patients with initial smear-positive pulmonary tuberculosis, and analyze its clinical effect. Method: 300 patients with initial smear-positive pulmonary tuberculosis were randomly divided into 2 groups,150 cases in each group. Routine management group patients were treated with normal management, and family steering chemotherapy management group patients were treated with family steering chemotherapy management on the basis of routine management. The medication compliance rate and cure rate of two groups were compared.Result: The compliance rate of family medication of steering chemotherapy management group was obviously higher than that of routine management group,the difference was statistically significant ( χ2=9.549,P<0.05). The cure rate of family steering chemotherapy management group was obviously higher than that of routine management group,the difference was statistically significant ( χ2=9.959,P<0.05).Conclusion: Family steering chemotherapy management could obviously increase the medication compliance and curative rate of initial smear-positive tuberculosis patients, reduce the generation of drug-resistant mycobacterium tuberculosis, and effectively promote tuberculosis patients’ rapid recovery.
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