补肾健脾法对卵巢功能围早衰患者卵巢储备功能影响

摘要

Objective:To study the effect of traditional Chinese method of kidney and spleen nourishing on the ovarian reserve function of patients with premature ovarian failure.Method:The clinical data of 110 patients with premature ovarian failure who had received treatment in our hospital from February 2015 to February 2016 were analyzed retrospectively.These patients were divided into two groups in accordance with the clinical treatment options,48 patients were treated with hormone artificial cyclic therapy as the control group,whereas the other 62 cases were given kidney and spleen nourishing for treatment as the observation group,the ovarian reserve function and immune function in the two groups were compared.Result:The E2 and FSH levels in the H region of patients in the observation group were improved after treatment,whereas the FSH level was (34.15±15.50)IU/L,lower than the (50.58±18.39)IU/L in control group,and the differences were statistically significant(P<0.01). The E2 and FSH levels secreted in the L region of patients in the observation group were improved than before treatment compared with the control group,the differences were statistically significant(P<0.01).Moreover,the average volume of ovary,uterine volume and endometrial thickness in the observation group were better than those in control group,the differences were statistically significant(P<0.01).T cell subsets were improved in both groups after treatment,and the differences were statistically significant(P<0.01).Conclusion:For patients with premature ovarian failure,kidney and spleen nourishing therapy can promote their ovarian reserve function and immune function,thus with certain clinical application and research value.%目的：研究卵巢功能围早衰应用补肾健脾法治疗对患者卵巢储备功能的影响。方法：资料选取2015年2月-2016年2月本院收治的卵巢早衰患者110例予以回顾性分析，按照临床所用不同治疗方案分为两组，将行激素人工周期治疗的48例患者作为对照组，将行补肾健脾法治疗的62例患者作为观察组，对两组的卵巢储备功能和免疫功能进行对比。结果：观察组治疗后H区E2、FSH水平均比治疗前改善，FSH水平为（34.15±15.50）IU/L低于对照组的（50.58±18.39）IU/L，差异有统计学意义（P<0.01）；观察组治疗后L区内分泌E2、LH与FSH水平均比治疗前和对照组改善，差异均有统计学意义（P<0.01）；同时观察组卵巢平均体积、子宫体积、子宫内膜厚度均优于对照组，差异均有统计学意义（P<0.01）；两组治疗后T细胞亚群均比治疗前改善，差异均有统计学意义（P<0.01）。结论：卵巢功能围早衰患者应用补肾健脾法治疗能够促进卵巢储备功能和免疫功能改善，具有一定的临床应用与研究价值。