无创正压通气在抢救重度急性左心衰合并Ⅱ型呼吸衰竭中的临床效果

摘要

目的：探讨无创正压通气治疗重度急性左心衰合并Ⅱ型呼吸衰竭的效果。方法：选取2014年3月-2016年1月本院收治的86例重度急性左心衰合并Ⅱ型呼吸衰竭患者作为研究对象，根据随机数字法分为对照组和观察组，每组43例。对照组采用常规抗心衰治疗，观察组在对照组基础上选用无创正压通气治疗。检测并比较两组患者治疗前、治疗10、24、48 h血浆N末端脑钠肽前体（NT-proBNP）和高敏C-反应蛋白（hs-CRP）的含量。结果：两组治疗后10、24、48 h NT-proBNP和hs-CRP均较治疗前降低，且观察组均低于对照组，比较差异均有统计学意义（P<0.05）。结论：无创正压通气治疗能够明显改善重度急性左心衰合并Ⅱ型呼吸衰竭患者的基本生命体征，缓解炎症。%Objective:To study the effect of noninvasive positive pressure ventilation in treatment with severe acute left heart failure combined with typeⅡ respiratory failure.Method:From March 2014 to January 2016,86 cases of severe acute left heart failure combined with type Ⅱ respiratory failure were selected as the research objects, they were divided into the control group and the observation group according to the random numbers,each group had 43 cases.The control group were treated with normal heart failure treatment,the observation group were treated with noninvasive positive pressure ventilation.Before treatment,10,24,48 h in treatment plasma N-terminal brain natriuretic peptide(NT-proBNP) and high-sensitivity C-reactive protein(hs-CRP) content of two groups were detected and compared.Result:The two groups after treatment 10,24,48 h NT-proBNP and hs-CRP were lower than before treatment,the observation group was lower than the control group,the differences were statistically significant(P<0.05).Conclusion:Noninvasive positive pressure ventilation therapy can significantly improve severe acute left heart failure combined with type Ⅱ respiratory failure basic vital signs and alleviate inflammation.